NASP (Nucleic Acid Structures Predictor) is a computer program that will allow predict the most evolutionarily conserved secondary structures evident within a set of aligned nucleic acid sequences. It will progressively identify all of the most probable secondary structures that display some degree of sequence conservation between sequences in an analysed alignment. Although NASP is distributed as source code it can also be used via a user friendly web-interface.
- NASP web server
Click here to submit your job.
- Getting help
NASP can be downloaded from the download page.
J. Y. Semegni; M. Wamalwa; R. Gaujoux; G. W. Harkins; A. Gray; D. P. Martin
NASP: A parallel program for identifying evolutionarily conserved nucleic acid secondary structures from nucleotide sequence alignments. Bioinformatics; Bioinformatics; 2011 27: 2443-2445.
NASP intensivelly uses UNAFOLD, please also cite the following reference when using NASP:
Markham,N.R. and Zuker,M. (2008)
UNAFold: software for nucleic acid folding and hybridization.
Methods Mol Biol., 453:3-31.