Assigning Estimated Signature to Real Cell-Types

Description

Assigns and reorder basis components to a cell type based on the proportion of cell-specific markers that contribute the most to each component.

match.cell is an alias for match.nmf

Usage

match.nmf(object, reference, n = NA)

match.cell(object, reference, n = NA)

Arguments

object: an NMF object
reference: a list of markers, usually a MarkerList object.
n: the number of markers to use per cell-type to actually assign the components

Value

object with the basis components reordered -- and renamed -- according to the computed assigned cell-types.