I am a mathematical population geneticist whose research focuses on analysing genome wide patterns of variation within and between species to address fundamental questions in biology, anthropology, and medicine. I am Senior Lecturer at the division of Human Genetics,IDM, Department of pathology within the University of Cape Town.
Senior lecturer in Bioinformatics, Computational population genetics and Computational Genomics.
My current research focuses are on on the computational and statistical methods for uncovering the genetics and environment architecture of genetic diseases, variation in drug/treatment response and investigating and developing various methodologies and tools to improve the analysis of large scale next generation sequencing and genomic studies such as genome-wide association studies or fine-mapping studies and , medical population genetics. Areas of interest include.
1. Genetic variation and human evolution, with particular interest in understanding the genetic diversity of African populations and multi-way mixed ancestry populations.
2. Functional components of heritability and heritability of human traits using next generation sequencing.
3. Generation and analysis of biological functional interaction networks.
4. Disease mapping in structured and mixed ancestry populations.
5. Common versus rare variant architectures of complex traits.
6. Computational approach for genomics association of drug/dosage responses, and genetics adaptation of human microbiomes.
7. Computational methods for the evolution of the diseases and their management.
8. Computational personalized genomic.
Masters and PhD opportunities in the above topics,
contact Dr. Chimusa: emile.chimusa.AT.uct.ac.za